Natasha Gherchcovsky de visita en el Lab

Desde el lunes 2 de abril del año en curso, y durante un mes, se encontrará realizando una pasantía de investigación la Srta. Natasha Gherchcovsky, estudiante de 6to. año de medicina de la Universidad Nacional de Rosario (UNR), Argentina. Si bien esta actividad está bajo el amparo de un convenio marco de cooperación entre la […]

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MYoung

Nobel Prize in Medicine

Dr. Young studies circadian clocks, which are endogenous mechanisms that time the recurring, daily activities observed in most organisms. Young’s research has shown how interactions among certain genes and their proteins produce molecular oscillations at the level of individual cells. These cellular clocks are active in most animal tissues and establish overt, circadian rhythms in […]

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phytochemical-1

Redox Biology of Skin Aging and Carcinogenesis: the Role of Natural Antioxidants as Potential Protective Agents

About this Research Topic Promoting healthy human ageing is one of the most important challenges and opportunities of the 21st century worldwide. Photodamage of the skin caused by acute or chronic sun exposure leading to premature skin aging and cancers has become important dermatological problems associated with high cost of treatment and skin care. Oxidative […]

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Clustering according to urolithin metabotype explains the interindividual variability in the improvement of cardiovascular risk biomarkers in overweight-obese individuals consuming pomegranate: A randomized clinical trial

Abstract Scope The pomegranate lipid-lowering properties remain controversial, probably due to the interindividual variability in polyphenol (ellagitannins) metabolism. Objective We aimed at investigating whether the microbially derived ellagitannin-metabolizing phenotypes, i.e. urolithin metabotypes A, (UM-A), B (UM-B), and 0 (UM-0), influence the effects of pomegranate extract (PE) consumption on 18 cardiovascular risk biomarkers in healthy overweight-obese […]

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metformin

Placing the nuclear pore in the metformin mechanism of action

Metformin is a drug that alters cellular metabolism and that is used to treat type 2 diabetes and may also be beneficial in treating cancer. To investigate the mechanism of action for metformin, Wu et al. used the model organism Caenorhabditis elegans and identified the C. elegans ortholog of acyl-CoA dehydrogenase 10 (CeACAD10) as a […]

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ohsumi

Nobel de Medicina 2016

El japonés Yoshinori Ohsumi (Fukuoka, 1945) ha sido galardonado hoy con el premio Nobel de Medicina por el descubrimiento de los mecanismos de la autofagia, el sistema de reciclaje del organismo. La palabra autofagia tiene su origen en el idioma griego y quiere decir “comerse a uno mismo”. El concepto emergió durante la década de […]

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alzheimer

Droga contra el Alzhéimer muestra resultados prometedores en pequeño ensayo

Un nuevo ensayo de una droga que algunos investigadores están calificando como “el más prometedor” en la lucha contra el Alzhéimer sugiere que puede ser posible limpiar el cerebro de la proteína amieloide que es característica de la enfermedad. El estudio fue pequeño y los investigadores advierten que es demasiado pronto para cantar victoria contra una […]

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furchgott_robert

Robert Furchgott

  A Nobel prizewinner, he showed how nitric oxide affects blood flow Nitric oxide, one of the simplest molecules on the planet, was once known simply as a pollutant from cigarettes and car exhausts. But in 1992 the journal Science nominated it as molecule of the year, following the discovery that it plays a vital […]

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